{"id":72,"date":"2020-04-27T07:55:00","date_gmt":"2020-04-27T06:55:00","guid":{"rendered":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/2020\/04\/27\/covid19-the-good-bad-and-ugly\/"},"modified":"2021-03-24T09:29:51","modified_gmt":"2021-03-24T09:29:51","slug":"covid19-the-good-bad-and-ugly","status":"publish","type":"post","link":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/2020\/04\/27\/covid19-the-good-bad-and-ugly\/","title":{"rendered":"COVID19  &#8211; The Good Bad and Ugly"},"content":{"rendered":"<p><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><b>The Good:<\/b><\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Let&#8217;s start with the good. Why not?<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Despite the pain of lockdown, the advantages of isolation go beyond reducing COVID19 cases to a level the NHS can manage.&nbsp;<\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">&nbsp;<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Not only has the NHS, so far, been heroically successful&nbsp;in managing the workload, they are learning as they go along, and quickly. I wondered how this might play out when&nbsp;reflecting&nbsp;on my time looking after babies needing&nbsp;ventilation&nbsp;for Respiratory Distress (also due to lack of the lung surfactant needed keep the alveoli open) on Special Care Baby Unit in the 1980&#8217;s. In terms of&nbsp;technology those days might as well have be in the stone age. There wasn&#8217;t one computer in the hospital at that time, and a mobile phone was the size of a breeze block.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Nevertheless even&nbsp;during&nbsp;my two years of involvement there, techniques for ventilation moved on rapidly. Basically from energetic ventilation to keep the babies gas measurements normal, to carefully using the smallest pressures and oxygen for the least amount of time possible. This significantly reduced the damage done to the babies lungs. <a href=\"https:\/\/www.webmd.com\/lung\/news\/20200415\/ventilators-helping-or-harming-covid-19-patients#1\">Might something&nbsp;similar&nbsp;be happening with COVID19<\/a>?<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">The need for&nbsp;ventilators&nbsp;was predicted on the basis of the first experiences in China, and the&nbsp;procurement scramble reflected the assumption that many hospital cases would need them. It seems now that we are&nbsp;ventilating&nbsp;less patients that initially expected and&nbsp;learning&nbsp;fast that COVID19 is <a href=\"https:\/\/www.medscape.com\/viewarticle\/928236#vp_2\">new<\/a>&nbsp;and <a href=\"https:\/\/www.atsjournals.org\/doi\/pdf\/10.1164\/rccm.202003-0817LE\">different from<\/a> previous experience of viral pneumonia and Adult Respiratory Distress Syndrome. Patients, it seems, are less clinically unwell than their oxygen saturation levels would, in normal situations, imply.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">The upshot of this is the good news. I suspect that more people, like Boris Johnson, will be&nbsp;getting&nbsp;by with close monitoring and support, nasal oxygen, or Continual Positive Airways pressure. <a href=\"https:\/\/en.wikipedia.org\/wiki\/Continuous_positive_airway_pressure\">(CPAP)<\/a>. This is&nbsp;rather&nbsp;like the sensation of&nbsp;breathing&nbsp;into a strong wind, which helps keep the airways open and can reduce the need for ventilation. If ventilation is needed, then I&#8217;m sure with experience, the outcome from this will improve too. Rather awkwardly for staff ventilating patients, the prone position seems to help.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">In summary, there is alot of learning going on about this novel condition and the message to delay infection and get COVID ready by maximising health and fitness remains as important as ever.&nbsp;<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><b>The Bad&#8230;<\/b><\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Never believe the <a href=\"https:\/\/edition.cnn.com\/2020\/04\/16\/health\/coronavirus-remdesivir-trial\/index.html\">hype<\/a>! I had hopes that Remdesivir would offer treatment for COVID19, with lots of expectation and no doubt <a href=\"https:\/\/chart.hl.co.uk\/charts\/chart.jsproto_large.chart?ID_SEDOL=2369174&amp;WIDTH=568&amp;HEIGHT=262&amp;TIME_SPAN=1Y&amp;SUBSAMPLINGGRANULARITY=DAY&amp;XAXISCLOSECOL=0&amp;LINE_WIDTH=1&amp;MOUNTAIN_COLOR1=a5b9d8&amp;MOUNTAIN_COLOR2=c1cfe5&amp;MOUNTAIN_COLOR3=c1cfe5&amp;MOUNTAIN_COLOR4=ffffff&amp;ID_NOTATION_COLOR1=25456b\">increased share price for Gilead<\/a>, the American drug company who hold its patents. Early reports of its &#8216;compassionate&#8217; use in France and the US led us to believe that the knights in shining armour might be on their way; only to be dashed once again by the harsh reality delivered by properly controlled randomised controlled trials.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">There are shenanigans though. The <a href=\"https:\/\/time.com\/5826618\/remdesivir-leaked-data-who-website\/\">report of its failure<\/a> was posted by the WHO and then removed, as it had &#8216;not been peer reviewed&#8217;. This won&#8217;t detract from the reality that the trial failed to show any benefit.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">It also turns out that the asymptomatic phase of COVID19 is significant enough for rapid spread outside the confines of lockdown or isolation, <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMe2009758?query=recirc_curatedRelated_article\">even in a skilled nursing home<\/a>. Again this means that after the lockdown there are likely to be more waves of infection and so once again the message is to get COVID ready.&nbsp;<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><b>The Ugly&#8230;<\/b><\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">The <a href=\"https:\/\/www.bbc.co.uk\/news\/world-us-canada-52399464\">Trumpster<\/a> and <a href=\"https:\/\/www.theguardian.com\/world\/2020\/mar\/23\/brazils-jair-bolsonaro-says-coronavirus-crisis-is-a-media-trick\">Bolsanaro<\/a> are making fools of themselves. Despite their power and influence, they seem not to understand the nature of responsibility. Their statements are verging on the comic, if it were not for their lofty positions.<\/span><\/p>\n<p><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">They exhibit a deadly combination of ignorance and total self confidence. Surely these characteristics will not be affordable as we come out of this crisis, whenever that might be. I read so much high quality comment from genuinely clever people, health staff, scientists, reporters, and ordinary&nbsp;people which are in the main, so inspiring. Then there are these two!<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Of course, Trump states that he was only &#8216;being sarcastic&#8221;. It didn&#8217;t look like it at the time. This sort of evasion reminds me of school. Or was it pre-school. On second thoughts no. Pre-school children have far more dignity and composure.<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\">Keep healthy!&nbsp;<\/span><br \/><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><span style=\"font-family: &quot;arial&quot; , &quot;helvetica&quot; , sans-serif;\"><br \/><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Good:Let&#8217;s start with the good. Why not?Despite the pain of lockdown, the advantages of&hellip; <a href=\"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/2020\/04\/27\/covid19-the-good-bad-and-ugly\/\" class=\"more-link btn btn-link\">Read More&hellip; <span class=\"screen-reader-text\">Continue reading COVID19  &#8211; The Good Bad and Ugly<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","footnotes":""},"categories":[21],"tags":[],"class_list":["post-72","post","type-post","status-publish","format-standard","hentry","category-pandemic-management"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/72","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/comments?post=72"}],"version-history":[{"count":1,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/72\/revisions"}],"predecessor-version":[{"id":661,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/72\/revisions\/661"}],"wp:attachment":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/media?parent=72"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/categories?post=72"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/tags?post=72"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}