{"id":70,"date":"2020-04-30T11:14:00","date_gmt":"2020-04-30T10:14:00","guid":{"rendered":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/2020\/04\/30\/hope-for-treatment-remdesivir-revisited\/"},"modified":"2021-03-24T09:29:40","modified_gmt":"2021-03-24T09:29:40","slug":"hope-for-treatment-remdesivir-revisited","status":"publish","type":"post","link":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/2020\/04\/30\/hope-for-treatment-remdesivir-revisited\/","title":{"rendered":"Hope for treatment? Remdesivir revisited."},"content":{"rendered":"

I posted regarding Remdesivir, an anti-viral drug which had showed early promising effects <\/a>for COVID. This showed shortening of the recovery time from 15 to 11 days and a reduction in mortality from 11 to 8%. So, any talk of a ‘cure’ is mis-placed, hopefully it might help.<\/span>

<\/span>Unfortunately, it showed no benefit in a subsequent trial in China. This was inadvertently posted by the WHO, noticed by the worlds press, and then quickly removed for peer review. Now it’s been published in the Lancet.<\/a> <\/span><\/p>\n

Today I read that hopes for this treatment are alive and well<\/a>, at least for the moment. It seems that Gilead are now pressing ahead with larger longer trials of the intravenous drug and for better end-points. The results will be eagerly awaited.  <\/span>

<\/span>It may be that Remdesivir will find a role, perhaps even in combination with other drugs as the results of trials come in. COVID science is moving along at an incredible pace. Patients and patience are needed.<\/span>

<\/span>One disadvantage is that it’s an intravenous drug with implications for its use and availability for most of the world, las well as its cost. <\/span>

<\/span>The other issue is whether, like many anti virals (and MS drugs) it will be more effective if administered  early and to at-risk patients with milder illness. Personally I think this likely to be the case but makes the issues of administration and cost loom larger still.<\/span>

<\/span>In any case, until the trial results roll in, hope springs eternal. <\/span>

<\/span>Watch this space!<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

I posted regarding Remdesivir, an anti-viral drug which had showed early promising effects for COVID. This showed… Read More… Continue reading Hope for treatment? Remdesivir revisited.<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","footnotes":""},"categories":[21],"tags":[],"class_list":["post-70","post","type-post","status-publish","format-standard","hentry","category-pandemic-management"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/70","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/comments?post=70"}],"version-history":[{"count":1,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/70\/revisions"}],"predecessor-version":[{"id":660,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/posts\/70\/revisions\/660"}],"wp:attachment":[{"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/media?parent=70"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/categories?post=70"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drbannonsblog.aprendo.co.uk\/drbannonsblog_wp\/wp-json\/wp\/v2\/tags?post=70"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}